Two sample MR report
ZSWIM7_Dendritic Cell (DC) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.4462290 | 0.7430060 | 0.6091175 |
| Weighted median | 4 | -0.1028961 | 0.0364667 | 0.0047778 |
| Inverse variance weighted | 4 | -0.1091138 | 0.0298192 | 0.0002530 |
| Simple mode | 4 | -0.0893213 | 0.0496668 | 0.1699500 |
| Weighted mode | 4 | -0.0886496 | 0.0479021 | 0.1613219 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1060704 | 2 | 0.9483466 |
| Inverse variance weighted | 0.6656189 | 3 | 0.8812593 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.2956204 | 0.3951987 | 0.5324402 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.52e-05 | 0 | TRUE | 0.4837967 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
